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Article

Identification of genes containing expanded purine repeats in the human genome and their apparent protective role against cancer.

Journal of biomolecular structure & dynamics - 1 Jan 2016

Singh Himanshu Narayan, Rajeswari Moganty R

Abstract excerpt

Purine repeat sequences present in a gene are unique as they have high propensity to form unusual DNA-triple helix structures. Friedreich's ataxia is the only human disease that is well known to be associated with DNA-triplexes formed by purine repeats. The purpose of this study was to recognize the expanded purine repeats (EPRs) in human genome and find their correlation with cancer pathogenesis. We developed...

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Source

Identifiers

PMID: 25990537
DOI: 10.1080/07391102.2015.1049553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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