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Article

Functional characterization of four allelic variants of human cytochrome P450 1A2.

Archives of biochemistry and biophysics - 1 Feb 2004

Zhou Huijia, Josephy P David, Kim Donghak, Guengerich F Peter

Abstract excerpt

Human cytochrome P450 1A2 catalyzes important reactions in xenobiotic metabolism, including the N-hydroxylation of carcinogenic aromatic amines. In 2001, Chevalier et al. reported four new P450 1A2 sequence variants in the human population. We have now expressed these variants in Escherichia coli...

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Identifiers

PMID: 14725854
DOI: 10.1016/j.abb.2003.11.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14725854-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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