Article
Protection against wild-type murine gammaherpesvirus-68 latency by a latency-deficient mutant.
The Journal of general virology - 1 Jan 2004
Boname Jessica M, Coleman Heather M, May Janet S, Stevenson Philip G
Abstract excerpt
A murine gammaherpesvirus-68 (MHV-68) mutant with deregulated transcription of its ORF50 transactivator was severely impaired in latency establishment. The deregulated virus showed reduced immunogenicity, probably reflecting a lower antigen load. However, it still elicited effective immunity to a...
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