Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variability of von Willebrand factor and risk of coronary heart disease: the Rotterdam Study.

British journal of haematology - 1 Feb 2004

van der Meer Irene M, Brouwers Geert-Jan, Bulk Saskia, Leebeek Frank W G, van der Kuip Deirdre A M, Hofman Albert, Witteman Jacqueline C M, Gómez García Encarnación B

Abstract excerpt

The von Willebrand factor (VWF) may be causally associated with coronary heart disease (CHD) or merely be a marker of endothelial damage. The G allele of the -1793 C/G promoter polymorphism in the VWF gene has been associated with higher plasma levels of VWF. To investigate whether VWF has a causal role in CHD, we designed a case-cohort study, including 352 subjects with CHD and a random cohort (n = 736), and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure Determination
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Disease

Share to Health Surveys

Share to Hemostasis

Share to Proportional Hazards Models

Share to Thrombosis

Share to von Willebrand Factor

Source

Identifiers

PMID: 14717782
DOI: 10.1046/j.1365-2141.2003.04776.x

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variability of von Willebrand factor and risk of coronary heart disease: the Rotterdam Study.PMID 14717782Read ↗

von Willebrand factor plasma levels, genetic variations and coronary heart disease in an older population.Semantic proximity Read ↗

A single nucleotide polymorphism at nucleotide -1793 in the von Willebrand factor (VWF) regulatory region is associated with plasma VWF:Ag levels.Semantic proximity Read ↗

Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease.Semantic proximity Read ↗

Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data.Semantic proximity Read ↗

Genetic determinants of von Willebrand factor plasma levels and the risk of stroke: the Rotterdam Study.Semantic proximity Read ↗

Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review.Semantic proximity Read ↗

Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosisSemantic proximity Read ↗

Coagulation factor VII gene haplotypes, obesity-related traits, and cardiovascular risk in young women.Semantic proximity Read ↗

Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.Semantic proximity Read ↗

Genetic determinants of activated factor VII-antithrombin plasma levels and mortality in patients with coronary artery disease.Semantic proximity Read ↗

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.Semantic proximity Read ↗

Correlation of von Willebrand factor gene polymorphism and coronary heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.