Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease.

Blood - 27 Jan 2011

van Schie Marianne C, de Maat Moniek P M, Isaacs Aaron, van Duijn Cornelia M, Deckers Jaap W, Dippel Diederik W J, Leebeek Frank W G

Abstract excerpt

High levels of von Willebrand factor (VWF) are associated with an increased risk for cardiovascular disease (CVD). Although VWF levels are strongly heritable and genetic susceptibility is an important risk factor for CVD, information on the contribution of common VWF gene variants to VWF levels a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cardiovascular Diseases
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to von Willebrand Factor

Share to Young Adult

Source

Identifiers

PMID: 20940418
DOI: 10.1182/blood-2010-03-273961

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20940418-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease.PMID 20940418Read ↗

von Willebrand factor plasma levels, genetic variations and coronary heart disease in an older population.Semantic proximity Read ↗

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.Semantic proximity Read ↗

Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort.Semantic proximity Read ↗

Unraveling the Influence of Common von Willebrand factor variants on von Willebrand Disease Phenotype: An Exploratory Study on the Molecular and Clinical Profile of von Willebrand Disease in Spain Cohort.Semantic proximity Read ↗

Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding.Semantic proximity Read ↗

Genetic determinants of von Willebrand factor plasma levels and the risk of stroke: the Rotterdam Study.Semantic proximity Read ↗

The common VWF single nucleotide variants c.2365A>G and c.2385T>C modify VWF biosynthesis and clearance.Semantic proximity Read ↗

CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease.Semantic proximity Read ↗

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.Semantic proximity Read ↗

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.Semantic proximity Read ↗

Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.Semantic proximity Read ↗

Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.