Article
The efavirenz-induced increase in HDL-cholesterol is influenced by the multidrug resistance gene 1 C3435T polymorphism.
AIDS (London, England) - 18 Feb 2005
Alonso-Villaverde Carlos, Coll Blai, Gómez Federico, Parra Sandra, Camps Jordi, Joven Jorge, Masana Lluis
Abstract excerpt
Efavirenz treatment has been associated with increases in HDL-cholesterol concentrations, and the circulating levels of the drug have been related to the multidrug resistance gene 1 (MDR-1) C3435T polymorphism. The changes in the measured lipid parameters were evaluated in 59 HIV-infected patients initiating efavirenz-based treatment at baseline and at 12 months of follow-up. Efavirenz treatment increased...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
