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Article

A neurobehavioral screening of the ckr mouse mutant: implications for an animal model of schizophrenia.

Brain research bulletin - 15 Jan 2004

Torres German, Hallas Brian H, Vernace Vita A, Jones Craig, Gross Kenneth W, Horowitz Judith M

Abstract excerpt

A model of schizophrenia, the chakragati (ckr) mouse was serendipitously created as a result of a transgenic insertional mutation. The apparent loss-of-function of an endogenous gene produced mice that, when homozygous, displayed an abnormal circling behavior phenotype. To determine whether this phenotype could be corrected by atypical antipsychotics, we compared the effects of clozapine and olanzapine on...

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Identifiers

PMID: 14709346
DOI: 10.1016/j.brainresbull.2003.09.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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