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Article

Behavioral phenotypes for negative symptoms in animal models of schizophrenia.

Journal of pharmacological sciences - 1 Jan 2014

Miyamoto Yoshiaki, Nitta Atsumi

Abstract excerpt

A devastating psychiatric disorder, schizophrenia is characterized by three major symptoms, positive and negative symptoms and cognitive deficit. Almost all current therapeutic drugs for schizophrenia have efficacy for positive symptoms, and weak efficacy for negative and cognitive deficit. In particular, social withdrawal, diminished motivation, and anhedonia as the depressive aspects of negative symptoms are...

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Identifiers

PMID: 25409784
DOI: 10.1254/jphs.14R02CR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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