Article
Ventricular size mapping in a transgenic model of schizophrenia.
Brain research. Developmental brain research - 1 Jan 2005
Torres German, Meeder Beth A, Hallas Brian H, Spernyak Joseph A, Mazurchuk Richard, Jones Craig, Gross Kenneth W, Horowitz Judith M
Abstract excerpt
Genetically engineered mice have been generated to model a variety of neurological disorders. The chakragati (ckr) mouse is beginning to provide valuable insights into the structural brain changes underlying certain manifestations of schizophrenia. For instance, these mice show enlargement of the lateral ventricles, an abnormality frequently reported as a structural aberration in the schizophrenic brain. As...
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