Article
[The methodological specificity of PCR-test of gene p53 in plasma and blood cell DNA of oncological patients].
Klinicheskaia laboratornaia diagnostika - 1 Nov 2003
Bartnovskiĭ A E, Belokhvostov A S, Abramov A A, Likhin F A
Abstract excerpt
The evaluation of mutations in the p53 gene is of a big value for the laboratory diagnostics in oncology. The p53 gene was analyzed, within the present case study, in blood plasma, in which tumor-origin DNAs were detected, as well as in blood cells and in tumor tissue. Optimal conditions were defined for polymerase chain reaction (PCR) with primers. The adequacy of the conditions selected for PCR and for...
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