TP53 gene mutations in plasma DNA of cancer patients.

Article

TP53 gene mutations in plasma DNA of cancer patients.

Genes, chromosomes & cancer - 1 Feb 1999

Silva J M, Gonzalez R, Dominguez G, Garcia J M, España P, Bonilla F

Abstract excerpt

Using different molecular techniques, DNA has been shown to be present in plasma of patients with several types of tumors. Mutations of TP53 are the most common genetic changes in human cancers. We investigated the presence of TP53 gene mutations in plasma DNA of breast and small cell lung cancer...

Topics

Breast Neoplasms
DNA, Neoplasm
Genes, p53
Humans
Lung Neoplasms
Mutation

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