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Article

TP53 gene mutations in plasma DNA of cancer patients.

Genes, chromosomes & cancer - 1 Feb 1999

Silva J M, Gonzalez R, Dominguez G, Garcia J M, España P, Bonilla F

Abstract excerpt

Using different molecular techniques, DNA has been shown to be present in plasma of patients with several types of tumors. Mutations of TP53 are the most common genetic changes in human cancers. We investigated the presence of TP53 gene mutations in plasma DNA of breast and small cell lung cancer patients. Tumor and plasma DNA of 25 patients were studied by PCR-SSCP and direct sequencing, through exons 5, 6, 7,...

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Identifiers

PMID: 9885984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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