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Article

Characterization of a novel B‐CLL candidate gene – <i>DLEU7</i> – located in the 13q14 tumor suppressor locus

5 Dec 2003

Abstract excerpt

Deletion of chromosome 13q14 is the most frequent genetic aberration in B-cell chronic lymphocytic leukemia (CLL), found in more than 50% of cases, indicating that this region contains a gene(s) involved in the development of CLL. However, the pathogenic gene in the critical 13q14 region has not yet been defined. Here, we have cloned and characterized a novel gene, DLEU7, located adjacent to the consensus deleted...

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PMID: 14706829
DOI: 10.1016/s0014-5793(03)01371-1

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