The pineapple eye gene is required for survival of Drosophila imaginal disc cells.

doi:10.1093/genetics/165.4.1869

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Article

The pineapple eye gene is required for survival of Drosophila imaginal disc cells.

Genetics - 1 Dec 2003

Shi Wei, Stampas Argyrios, Zapata Cynthia, Baker Nicholas E

Abstract excerpt

Each ommatidium of the Drosophila eye is constructed by precisely 19 specified precursor cells, generated in part during a second mitotic wave of cell divisions that overlaps early stages of ommatidial cell specification. Homozygotes for the pineapple eye mutation lack sufficient precursor cells due to apoptosis during the period of fate specification. In addition development is delayed by apoptosis during...

Topics

Amino Acid Sequence
Animals
Animals, Genetically Modified
Apoptosis
Cell Survival
Cloning, Molecular
Drosophila
Embryo, Nonmammalian
Eye
Eye Proteins
Female
Gene Expression Regulation, Developmental
Genes, Recessive
Heterozygote
Homozygote

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Identifiers

PMID: 14704172
DOI: 10.1093/genetics/165.4.1869
PMCID: PMC1462889

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Male

Molecular Sequence Data

Morphogenesis