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Article

Germline transformation using a prune cDNA rescues prune/killer of prune lethality and the prune eye color phenotype in Drosophila.

Genetics - 1 Dec 1996

Timmons L, Shearn A

Abstract excerpt

Null mutations in the prune gene of Drosophila melanogaster result in prune eye color due to reductions in red pigment accumulation. When one copy of the awd(Killer of prune) mutant gene is present in a prune background, the animals die. The cause of prune/Killer of prune lethality remains unknown. The genomic region characterized for the prune locus is transcriptionally active and complex, with multiple and...

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Identifiers

PMID: 8978047
DOI: 10.1093/genetics/144.4.1589
PMCID: PMC1207711

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