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Article

ATP binding cassette transporter A1--key roles in cellular lipid transport and atherosclerosis.

Molecular and cellular biochemistry - 1 Aug 2002

Srivastava Neelam

Abstract excerpt

ATP-binding cassette transporter A1 (ABCA1) was recently recognized as the mutant molecule responsible for Tangier disease with low HDL levels, accumulation of cholesteryl esters in tissues, and increased risk of cardiovascular disease. Extensive studies for the past 2 years have recognized the critical role of ABCA1 in cholesterol and phospholipid trafficking. Since the removal of cholesterol from tissues is a...

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Source

Identifiers

PMID: 12236582
DOI: 10.1023/a:1016506221047

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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ATP binding cassette transporter A1--key roles in cellular lipid transport and atherosclerosis.PMID 12236582Read ↗

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[The role of transmembrane lipidtransporter molecules in the atherosclerotic process].Semantic proximity Read ↗

ABCA1-deficient mice: insights into the role of monocyte lipid efflux in HDL formation and inflammation.Semantic proximity Read ↗

The Role of the ATP-Binding Cassette A1 (ABCA1) in Human Disease.Semantic proximity Read ↗

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