Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of the type 1 plasminogen activator inhibitor 4G/5G gene polymorphism to impaired fibrinolysis in vital exhaustion.

Italian heart journal : official journal of the Italian Federation of Cardiology - 1 Nov 2003

von Känel Roland, Maly Friedrich E, Frey Karl, Fischer Joachim E

Abstract excerpt

BACKGROUND: Inappropriate coping with chronic stress may result in a state of "vital exhaustion" that has been associated with coronary artery disease. Impaired fibrinolysis due to an increase in type 1 plasminogen activator inhibitor (PAI-1) might mediate this link. Genetic and environmental fac...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Constitution
Share to Cholesterol, LDL
Share to Fatigue

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrinolysis

Share to Glycated Hemoglobin

Share to Plasminogen Activator Inhibitor 1

Share to Serine Proteinase Inhibitors

Share to Statistics as Topic

Source

Identifiers

PMID: 14699709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14699709-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of the type 1 plasminogen activator inhibitor 4G/5G gene polymorphism to impaired fibrinolysis in vital exhaustion.PMID 14699709Read ↗

The 4G4G genotype of the plasminogen activator inhibitor 4G/5G gene polymorphism is associated with coronary atherosclerosis in patients at high risk for this disease.Semantic proximity Read ↗

Gender-specific association of the plasminogen activator inhibitor-1 4G/5G polymorphism with central arterial blood pressure.Semantic proximity Read ↗

Relationships between fibrinogen, plasminogen activator inhibitor-1, and their gene polymorphisms in current smokers with essential hypertension.Semantic proximity Read ↗

Regular exercise, plasminogen activator inhibitor-1 (PAI-1) activity and the 4G/5G promoter polymorphism in the PAI-1 gene.Semantic proximity Read ↗

PAI-1 plasma levels in a general population without clinical evidence of atherosclerosis: relation to environmental and genetic determinants.Semantic proximity Read ↗

The -675 4G/5G polymorphism at the Plasminogen Activator Inhibitor 1 (PAI-1) gene modulates plasma Plasminogen Activator Inhibitor 1 concentrations in response to dietary fat consumption.Semantic proximity Read ↗

The plasminogen activator inhibitor-1 (PAI-1) promoter haplotype is related to PAI-1 plasma concentrations in lean individuals.Semantic proximity Read ↗

Is the plasminogen activator inhibitor-1 gene a candidate gene predisposing to hypertension? Results from a population-based study in Spain.Semantic proximity Read ↗

4G/5G PAI-1 promoter polymorphism and acute-phase levels of PAI-1 following coronary bypass surgery: a prospective study.Semantic proximity Read ↗

Role of the 4G/5G polymorphism of PaI-1 gene promoter on PaI-1 levels in obese patients: influence of fat distribution and insulin-resistance.Semantic proximity Read ↗

4G/5G polymorphism modulates PAI-1 circulating levels in obese women.Semantic proximity Read ↗

Role of gender and genetic variance in plasminogen activator inhibitor-1 secretion from human adipose tissue.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.