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Article

4G/5G PAI-1 promoter polymorphism and acute-phase levels of PAI-1 following coronary bypass surgery: a prospective study.

Journal of thrombosis and thrombolysis - 1 Dec 2003

Burzotta Francesco, Iacoviello Licia, Di Castelnuovo Augusto, Zamparelli Roberto, D'Orazio Andria, Amore Concetta, Schiavello Rocco, Donati Maria Benedetta, Maseri Attilio, Possati GianFederico, Andreotti Felicita

Abstract excerpt

BACKGROUND AND OBJECTIVE: The 4G/5G plasminogen activator inhibitor-1 (PAI-1) promoter polymorphism has been associated with basal PAI-1 levels, with ischemic heart disease, and with adverse prognosis in critically ill patients. We hypothesized it might also influence the acute-phase levels of PAI-1 following coronary bypass surgery. METHODS: In 111 consecutive patients undergoing elective coronary bypass...

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Identifiers

PMID: 15087600
DOI: 10.1023/B:THRO.0000024052.79415.62

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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