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Article

Gender-specific association of the plasminogen activator inhibitor-1 4G/5G polymorphism with central arterial blood pressure.

American journal of hypertension - 1 Jul 2011

Björck Hanna M, Eriksson Per, Alehagen Urban, De Basso Rachel, Ljungberg Liza U, Persson Karin, Dahlström Ulf, Länne Toste

Abstract excerpt

BACKGROUND: The functional plasminogen activator inhibitor-1 (PAI-1) 4G/5G polymorphism has previously been associated with hypertension. In recent years, central blood pressure, rather than brachial has been argued a better measure of cardiovascular damage and clinical outcome. The aim of this study was to investigate the possible influence of the 4G/5G polymorphism on central arterial blood pressure in a cohort...

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PMID: 21490692
DOI: 10.1038/ajh.2011.63

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