Article
A promoter polymorphism rs2075824 within IMPA2 gene affecting the transcription activity: possible relationship with schizophrenia.
Journal of cellular and molecular medicine - 1 Apr 2017
Li Jia, Huang Sheng, Dai Hui-Rong, Wang Juan, Lin Li-Hui, Xiao Hui, Peng Xia, Li Fei, Wang Yu-Ping, Yuan Jian-Min, Li Li
Abstract excerpt
Previous studies with biological and genetic evidence indicate that the myo-inositol monophosphatase 2 (IMPA2) gene may influence schizophrenia. We performed a genetic association study in Han Chinese cohorts. Five single nucleotide polymorphisms within IMPA2 promoter region (rs971363, rs971362, rs2075824, rs111410794 and rs111610121), as well as one (, in intron 1) that was positively associated in...
