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Article

The alpha- and beta'-COP WD40 domains mediate cargo-selective interactions with distinct di-lysine motifs.

Molecular biology of the cell - 1 Mar 2004

Eugster Anne, Frigerio Gabriella, Dale Martin, Duden Rainer

Abstract excerpt

Coatomer is required for the retrieval of proteins from an early Golgi compartment back to the endoplasmic reticulum. The WD40 domain of alpha-COP is required for the recruitment of KKTN-tagged proteins into coatomer-coated vesicles. However, lack of the domain has only minor effects on growth in yeast. Here, we show that the WD40 domain of beta'-COP is required for the recycling of the KTKLL-tagged Golgi protein...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14699056
DOI: 10.1091/mbc.e03-10-0724
PMCID: PMC363058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The alpha- and beta'-COP WD40 domains mediate cargo-selective interactions with distinct di-lysine motifs.PMID 14699056Read ↗

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