Article
Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum.
Cell - 30 Dec 1994
Letourneur F, Gaynor E C, Hennecke S, Démollière C, Duden R, Emr S D, Riezman H, Cosson P
Abstract excerpt
Dilysine motifs in cytoplasmic domains of transmembrane proteins are signals for their continuous retrieval from the Golgi back to the endoplasmic reticulum (ER). We describe a system to assess retrieval to the ER in yeast cells making use of a dilysine-tagged Ste2 protein. Whereas retrieval was...
Topics
- Amino Acid Sequence
- Biological Transport
- Coatomer Protein
- Dipeptides
- Endoplasmic Reticulum
- Fungal Proteins
- Hexosyltransferases
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Protein Sorting Signals
- Receptors, Mating Factor
- Receptors, Peptide
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Transcription Factors
- Transferases