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Article

The ins and outs of transcriptional control: nucleocytoplasmic shuttling in development and disease.

Trends in genetics : TIG - 1 Jan 2004

Smith James M, Koopman Peter A

Abstract excerpt

Recent findings relating to SOX transcription factors indicate that defects in organogenesis can be caused not only by impairment of the biochemical properties of transcription factors but also, in some cases, by deficient nuclear import. In addition, experimentally interfering with the nuclear export signals of some SOX factors has now been found to cause developmental defects. Controlling the balance of nuclear...

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Identifiers

PMID: 14698613
DOI: 10.1016/j.tig.2003.11.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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