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Article

The COOH-terminal domain of agrin signals via a synaptic receptor in central nervous system neurons.

The Journal of cell biology - 9 Jun 2003

Hoover Cameron L, Hilgenberg Lutz G W, Smith Martin A

Abstract excerpt

Agrin is a motor neuron-derived factor that directs formation of the postsynaptic apparatus of the neuromuscular junction. Agrin is also expressed in the brain, raising the possibility that it might serve a related function at neuron-neuron synapses. Previously, we identified an agrin signaling pathway in central nervous system (CNS) neurons, establishing the existence of a neural receptor that mediates responses...

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Identifiers

PMID: 12796478
DOI: 10.1083/jcb.200301013
PMCID: PMC2172957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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