Article
Moenomycin-resistance is associated with vancomycin-intermediate susceptibility in Staphylococcus aureus.
Microbiology and immunology - 1 Jan 2003
Nishi Hiromi, Komatsuzawa Hitoshi, Yamada Sakuo, Fujiwara Tamaki, Ohara Masaru, Ohta Kouji, Sugiyama Masaru, Ishikawa Takenori, Sugai Motoyuki
Abstract excerpt
We have previously isolated a vancomycin-intermediate susceptibility mutant from methicillinresistant Staphylococcus aureus(MRSA) strain COL, and demonstrated the increased glycan-chain length and the decreased moenomycin-susceptibility. To further investigate the relationship between the resistance to vancomycin and to moenomycin, we isolated moenomycin-resistant mutants (4-16 fold higher compared to the parent)...
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