Article
A highly vancomycin-resistant laboratory mutant of Staphylococcus aureus.
FEMS microbiology letters - 1 Sept 1996
Sieradzki K, Tomasz A
Abstract excerpt
A resistant mutant with vancomycin MIC of 100 micrograms/ml was isolated relatively easily through step pressure in the laboratory from a Staphylococcus aureus strain with initial MIC of 1.5 micrograms/ml for the antibiotic. Upon addition of vancomycin (50 micrograms/ml) to the growth medium mass increase of the culture and peptidoglycan synthesis continued but cell division (daughter cell separation), cell wall...
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