Increase in glutamine-non-amidated muropeptides in the peptidoglycan of vancomycin-resistant Staphylococcus aureus strain Mu50.

doi:10.1093/jac/42.3.315

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Article

Increase in glutamine-non-amidated muropeptides in the peptidoglycan of vancomycin-resistant Staphylococcus aureus strain Mu50.

The Journal of antimicrobial chemotherapy - 1 Sept 1998

Hanaki H, Labischinski H, Inaba Y, Kondo N, Murakami H, Hiramatsu K

Abstract excerpt

The peptidoglycan compositions of vancomycin-resistant Staphylococcus aureus (VRSA) strain Mu50 (MIC 8 mg/L) and hetero-VRSA strain Mu3 (MIC 3 mg/L) were compared in order to understand the mechanism of vancomycin resistance. As compared with Mu3, the cell wall of Mu50 had increased amounts of gl...

Topics

Amino Acids
Drug Resistance, Microbial
Glutamine
Microbial Sensitivity Tests
Peptides
Peptidoglycan
Phenotype
Protein Conformation
Staphylococcus aureus
Vancomycin

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