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Article

Genetic alterations responsible for reduced susceptibility to vancomycin in community-associated MRSA strains of ST72.

The Journal of antimicrobial chemotherapy - 1 Sept 2017

Baek Jin Yang, Chung Doo Ryeon, Ko Kwan Soo, Kim So Hyun, Yang Soo-Jin, Kang Cheol-In, Peck Kyong Ran, Song Jae-Hoon

Abstract excerpt

Objectives: We previously reported the first case of vancomycin treatment failure due to development of vancomycin-intermediate resistance in a patient with an MRSA of ST72, a community genotype in Korea. We investigated two isogenic MRSA strains from this patient, who experienced treatment failure with vancomycin and rifampicin. Methods: We tracked the genetic alterations that confer reduced susceptibility to...

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PMID: 28595277
DOI: 10.1093/jac/dkx175

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