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Article

Fosfomycin: evaluation of the published evidence on the emergence of antimicrobial resistance in Gram-negative pathogens.

The Journal of antimicrobial chemotherapy - 1 Feb 2012

Karageorgopoulos Drosos E, Wang Rui, Yu Xu-Hong, Falagas Matthew E

Abstract excerpt

Fosfomycin has attracted renewed interest for the treatment of lower urinary tract and even systemic infections caused by Gram-negative pathogens with resistance to traditionally used agents. The main concern regarding the clinical utility of fosfomycin refers to the potential for the emergence of resistance during therapy. In this review, we evaluate the available published evidence regarding the mechanisms and...

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PMID: 22096042
DOI: 10.1093/jac/dkr466

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