Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a retinoid receptor response element in the human aldehyde dehydrogenase-2 promoter.

Alcoholism, clinical and experimental research - 1 Dec 2003

Pinaire Jane, Chou Wan-Yin, Morton Michael, You Min, Zeng Yan, Cho Won Kyoo, Galli Andrea, Everett Lynn, Breen Heather, Dumaual Natividad, Smith Jennifer R, Crabb David

Abstract excerpt

BACKGROUND: The human aldehyde dehydrogenase-2 promoter contains sites that bind members of the nuclear receptor family, and one (designated FP330-3') is predicted to bind retinoic acid receptors. METHODS: Binding of retinoid receptors to the FP330-3' oligonucleotide duplex and point mutations thereof was assayed using electrophoretic mobility shift assays. The function of the promoter element was determined in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldehyde Dehydrogenase
Share to Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Rabbits

Share to Receptors, Retinoic Acid

Share to Response Elements

Share to Retinoic Acid Receptor alpha

Source

Identifiers

PMID: 14691372
DOI: 10.1097/01.ALC.0000100941.86227.4F

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a retinoid receptor response element in the human aldehyde dehydrogenase-2 promoter.PMID 14691372Read ↗

Evaluation of aldehyde dehydrogenase 1 promoter polymorphisms identified in human populations.Semantic proximity Read ↗

An A/G polymorphism in the promoter of mitochondrial aldehyde dehydrogenase (ALDH2): effects of the sequence variant on transcription factor binding and promoter strength.Semantic proximity Read ↗

Alcohol dehydrogenase 2 is a major hepatic enzyme for human retinol metabolismSemantic proximity Read ↗

DHRS3, a retinal reductase, is differentially regulated by retinoic acid and lipopolysaccharide-induced inflammation in THP-1 cells and rat liverSemantic proximity Read ↗

trans activation of human alcohol dehydrogenase gene expression in hepatoma cells by C/EBP molecules bound in a novel arrangement just 5' and 3' to the TATA box.Semantic proximity Read ↗

ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1.Semantic proximity Read ↗

Transcriptional co-operativity between distant retinoic acid response elements in regulation of<i>Cyp26A1</i>inducibilitySemantic proximity Read ↗

Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3.Semantic proximity Read ↗

Identification of the human ApoAV gene as a novel RORalpha target gene.Semantic proximity Read ↗

Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.Semantic proximity Read ↗

Functional characterization of a natural retinoic acid responsive element.Semantic proximity Read ↗

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.