Article
Phosphorylation and recruitment of Syk by immunoreceptor tyrosine-based activation motif-based phosphorylation of tamalin.
The Journal of biological chemistry - 30 Jul 2004
Hirose Masayuki, Kitano Jun, Nakajima Yoshiaki, Moriyoshi Koki, Yanagi Shigeru, Yamamura Hirohei, Muto Takanori, Jingami Hisato, Nakanishi Shigetada
Abstract excerpt
Tamalin is a scaffold protein that forms a multiple protein assembly including metabotropic glutamate receptors (mGluRs) and several postsynaptic and protein-trafficking scaffold proteins in distinct mode of protein-protein association. In the present investigation, we report that tamalin possesses a typical immunoreceptor tyrosine-based activation motif (ITAM), which enables Syk kinase to be recruited and...
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