Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor.

Molecular and cellular endocrinology - 14 May 2010

Diefenbacher Markus E, Litfin Margarethe, Herrlich Peter, Kassel Olivier

Abstract excerpt

Trip6 belongs to a family of cytosolic LIM domain proteins involved in cell adhesion and migration. Recent findings show that these proteins also regulate transcription. We have previously reported that nTrip6, a nuclear isoform of Trip6, acts as a co-activator for AP-1 and NF-kappaB transcriptio...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATPases Associated with Diverse Cellular Activities
Share to LIM Domain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NF-kappa B

Share to Proteasome Endopeptidase Complex

Share to Proto-Oncogene Proteins c-fos

Share to Receptors, Glucocorticoid

Share to Transcription Factor AP-1

Share to Transcription Factor RelA

Source

Identifiers

PMID: 20153803
DOI: 10.1016/j.mce.2010.02.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20153803-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor.PMID 20153803Read ↗

Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contextsSemantic proximity Read ↗

Emerging roles for TNIP1 in regulating post-receptor signaling.Semantic proximity Read ↗

The HumanTRIP6Gene Encodes a LIM Domain Protein and Maps to Chromosome 7q22, a Region Associated with TumorigenesisSemantic proximity Read ↗

An emerging link between LIM domain proteins and nuclear receptorsSemantic proximity Read ↗

Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.Semantic proximity Read ↗

A LIM protein, Hic‐5, functions as a potential coactivator for Sp1Semantic proximity Read ↗

RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity.Semantic proximity Read ↗

Cell adhesion signals regulate the nuclear receptor activity.Semantic proximity Read ↗

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cellsSemantic proximity Read ↗

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.Semantic proximity Read ↗

TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor.Semantic proximity Read ↗

The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.