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Article

Brucella abortus rough mutants are cytopathic for macrophages in culture.

Infection and immunity - 1 Jan 2004

Pei Jianwu, Ficht Thomas A

Abstract excerpt

Rough mutants of Brucella spp. are attenuated for survival in animal models. However, conflicting in vitro evidence has been obtained concerning the intracellular survival of rough mutants. Transposon-derived rough mutants isolated in our laboratory were previously shown to exhibit small but significant reductions in intracellular survival in a 12-h in vitro assay. Several recent publications report that rough...

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Identifiers

PMID: 14688125
DOI: 10.1128/IAI.72.1.440-450.2004
PMCID: PMC343953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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