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Rough brucella strain RM57 is attenuated and confers protection against Brucella melitensis.

Microbial pathogenesis - 1 Jun 2017

Feng Yu, Peng Xiaowei, Jiang Hui, Peng Yong, Zhu Liangquan, Ding Jiabo

Abstract excerpt

Brucella melitensis (B. melitensis) is a facultative intracellular pathogen, which is the main epidemic strain in China. To overcome disadvantages of traditional live attenuated vaccines, in this study a rough mutant RM57 was induced from a B. melitensis isolate M1981. In order to uncover the reason of changes in the LPS of RM57, the nucleotide sequences and transcription levels of all known genes related to LPS...

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PMID: 28390976
DOI: 10.1016/j.micpath.2017.03.045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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