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Article

Transcriptomic analysis of smooth versus rough Brucella melitensis Rev.1 vaccine strains reveals insights into virulence attenuation.

International journal of medical microbiology : IJMM - 1 Jan 2020

Salmon-Divon Mali, Kornspan David

Abstract excerpt

Brucella melitensis Rev.1 is the live attenuated Elberg-originated vaccine strain of the facultative intracellular Brucella species, and is widely used to control brucellosis in small ruminants. However, Rev.1 may cause abortions in small ruminants that have been vaccinated during the last trimester of gestation, it is pathogenic to humans, and it induces antibodies directed at the O-polysaccharide (O-PS) of the...

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Identifiers

PMID: 31699441
DOI: 10.1016/j.ijmm.2019.151363

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