Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of gene expression in double-muscled and normal-muscled bovine embryos.

Animal genetics - 1 Dec 2003

Potts J K, Echternkamp S E, Smith T P L, Reecy J M

Abstract excerpt

Myostatin, a member of the transforming growth factor-beta superfamily, is a negative regulator of skeletal muscle growth. Cattle with mutations that inactivate myostatin exhibit a remarkable increase in mass of skeletal muscle called double muscling that is accompanied by an equally remarkable decrease in carcass fat. Although a mouse knockout model has been created which results in mice with a 200% increase in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cattle
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Muscle Proteins

Share to Muscle, Skeletal

Share to Nucleic Acid Hybridization

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 14687074
DOI: 10.1046/j.0268-9146.2003.01055.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of gene expression in double-muscled and normal-muscled bovine embryos.PMID 14687074Read ↗

Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle.Semantic proximity Read ↗

Target genes of myostatin loss-of-function in muscles of late bovine fetuses.Semantic proximity Read ↗

The myostatin gene: an overview of mechanisms of action and its relevance to livestock animals.Semantic proximity Read ↗

Myostatin knockout in bovine fetal fibroblasts by using TALEN.Semantic proximity Read ↗

Molecular expression of myostatin and MyoD is greater in double-muscled than normal-muscled cattle fetuses.Semantic proximity Read ↗

Functional effect of mir-27b on myostatin expression: a relationship in Piedmontese cattle with double-muscled phenotype.Semantic proximity Read ↗

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle.Semantic proximity Read ↗

Myostatin: a modulator of skeletal-muscle stem cellsSemantic proximity Read ↗

Global Long Noncoding RNA Expression Profiling of MSTN and FGF5 Double-Knockout Sheep Reveals the Key Gatekeepers of Skeletal Muscle Development.Semantic proximity Read ↗

Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct.Semantic proximity Read ↗

Skeletal muscle development in normal and double-muscled cattle.Semantic proximity Read ↗

Genomic organization and neonatal expression of the bovine myostatin gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.