Article
Molecular expression of myostatin and MyoD is greater in double-muscled than normal-muscled cattle fetuses.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 May 2001
Oldham J M, Martyn J A, Sharma M, Jeanplong F, Kambadur R, Bass J J
Abstract excerpt
Excessive muscling in double-muscled cattle arises from mutations in the myostatin gene, but the role of myostatin in normal muscle development is unclear. The aim of this study was to measure the temporal relationship of myostatin and myogenic regulatory factors during muscle development in normal (NM)- and double-muscled (DM) cattle to determine the timing and possible targets of myostatin action in vivo....
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