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Article

Verapamil reverses the ultrastructural alterations in the plasma membrane induced by drug resistance.

FEBS letters - 21 Dec 1992

García-Segura L M, Soto F, Planells-Cases R, Gonzalez-Ros J M, Ferragut J A

Abstract excerpt

Two P388 cell sublines with different levels of resistance to daunomycin (DNM), P388/20 and P388/100 cells (approximately 20- and 100-fold resistance, respectively), undergo a significant (approximately 2-fold) increase in the number of intramembrane particles (IMPs) present at their plasma membrane, as compared to that exhibited by the parental, drug-sensitive P388 (P388/S) cell line. Regardless of the level of...

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Identifiers

PMID: 1468576
DOI: 10.1016/0014-5793(92)81515-n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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