Ultrastructural appraisal of the multidrug resistance in K562 and LR73 cell lines from Fourier transform infrared spectroscopy.

Article

Ultrastructural appraisal of the multidrug resistance in K562 and LR73 cell lines from Fourier transform infrared spectroscopy.

Cancer research - 15 Aug 1993

Le Gal J M, Morjani H, Manfait M

Abstract excerpt

Two different cell lines sharing the multidrug resistance (MDR) phenotype were investigated for 8 months by means of Fourier transform IR spectroscopy on cell smears. We studied (a) a human leukemic doxorubicin-sensitive K562 cell line, from which a doxorubicin-resistant K562 cell subline was sub...

Topics

Animals
Cell Line
Cricetinae
Doxorubicin
Drug Resistance
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Phenotype
Spectrophotometry, Infrared
Tumor Cells, Cultured

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