Article
Specific Secondary Genetic Alterations in Mantle Cell Lymphoma Provide Prognostic Information Independent of the Gene Expression–Based Proliferation Signature
13 Feb 2007
Abstract excerpt
PURPOSE: To compare the genetic relationship between cyclin D1-positive and cyclin D1-negative mantle cell lymphomas (MCLs) and to determine whether specific genetic alterations may add prognostic information to survival prediction based on the proliferation signature of MCLs. PATIENTS AND METHODS: Seventy-one cyclin D1-positive and six cyclin D1-negative MCLs previously characterized by gene expression profiling...