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Article

Juvenile diet restriction and the aging and reproduction of adult Drosophila melanogaster.

Aging cell - 1 Dec 2003

Tu Meng-Ping, Tatar Marc

Abstract excerpt

Mutations of the insulin signal pathway in Drosophila melanogaster produce long-lived adults with many correlated phenotypes. Homozygotes of insulin-like receptor (InR) and insulin-like receptor substrate (chico) delay time to eclosion, reduce body size, decrease reproduction and increase life span. Because these mutations are expressed through all life stages it is unclear when insulin signals must be reduced to...

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Source

Identifiers

PMID: 14677635
DOI: 10.1046/j.1474-9728.2003.00064.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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