Article
Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions.
Development (Cambridge, England) - 1 Dec 1992
Bennett R L, Hoffmann F M
Abstract excerpt
Mutations in the Drosophila Abelson tyrosine kinase have pleiotropic effects late in development that lead to pupal lethality or adults with a reduced life span, reduced fecundity and rough eyes. We have examined the expression of the abl protein throughout embryonic and pupal development and ana...
Topics
- Animals
- Drosophila
- Embryonic Induction
- Eye
- Gene Expression
- Muscles
- Mutation
- Nervous System
- Phenotype
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins c-abl