Article
Susceptibility associations of HLA class II gene polymorphisms in oral submucous fibrosis derived oral squamous cell carcinoma.
Human immunology - 1 Apr 2026
Tan Yisi, Xiao Yao, Huang Xiaoqin, Liu Mina, You Chuang, Ye Yao, Tan Jin, Hu Chun
Abstract excerpt
OBJECTIVE: This study aimed to explore associations between human leukocyte antigen (HLA) class II (DRB1, DQB1, DPB1) alleles and haplotypes and susceptibility to oral submucous fibrosis (OSF) and its progression to oral squamous cell carcinoma (OSCC). METHODS: 54 OSF-derived OSCC patients, 53 OSF patients, and 56 healthy controls were enrolled. HLA class II genes were typed using polymerase chain...
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