Article
Endothelial protein C receptor 1651C/G polymorphism and soluble endothelial protein C receptor levels in women with idiopathic recurrent miscarriage.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2012
Dendana Maryam, Messaoudi Safia, Hizem Sondes, Jazia Khaled B, Almawi Wassim Y, Gris Jean-Christophe, Mahjoub Touhami
Abstract excerpt
High levels of soluble endothelial protein C receptor (EPCR) induce coagulation dysfunction by inhibiting protein C activation, and activated protein C (APC) activity. We tested whether EPCR 1651C/G promoter variant and changes in plasma soluble EPCR levels are risk factors for idiopathic recurrent spontaneous miscarriage (RSM). A case-control study involving 283 RSM cases and 380 age and BMI-matched control...
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