Article
Association of functional genetic variants of CTLA4 with reduced serum CTLA4 protein levels and increased risk of idiopathic recurrent miscarriages.
Fertility and sterility - 1 Oct 2016
Misra Maneesh Kumar, Mishra Aditi, Phadke Shubha R, Agrawal Suraksha
Abstract excerpt
OBJECTIVE: To determine whether idiopathic recurrent miscarriages (IRM) are associated with the alteration in serum CTLA4 protein levels and to evaluate their correlation with CTLA4 tag single-nucleotide polymorphisms (SNPs). DESIGN: Retrospective case-control study. SETTING: Tertiary-care referral hospital. PATIENT(S): Three hundred women with IRM (mean age: 28.6 ± 5.4 years) and 600 age-matched (mean age: 29.2...
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