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Article

An aromatic side chain is required at residue 8 of SU for fusion of ecotropic murine leukemia virus.

Journal of virology - 1 Jan 2004

Qian Zhaohui, Albritton Lorraine M

Abstract excerpt

The surface glycoprotein (SU) of most gammaretroviruses contains a conserved histidine at its amino terminus. In ecotropic murine leukemia virus SU, replacement of histidine 8 with arginine (H8R) or deletion of H8 (H8del) abolishes infection and cell-cell fusion but has no effect on binding to the cellular receptor. We report here that an aromatic ring side chain is essential to the function of residue 8. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14671131
DOI: 10.1128/jvi.78.1.508-512.2004
PMCID: PMC303429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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