pH-independent murine leukemia virus ecotropic envelope-mediated cell fusion: implications for the role of the R peptide and p12E TM in viral entry.

doi:10.1128/JVI.68.5.3220-3231.1994

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Article

pH-independent murine leukemia virus ecotropic envelope-mediated cell fusion: implications for the role of the R peptide and p12E TM in viral entry.

Journal of virology - 1 May 1994

Ragheb J A, Anderson W F

Abstract excerpt

Murine leukemia virus ecotropic and amphotropic envelope expression vectors were genetically engineered to generate truncations of the p15E TM cytoplasmic tail. The ecotropic construct CEET has the entire cytoplasmic tail of TM deleted, while the CEETR construct has only the R peptide portion of the tail deleted, thereby producing a TM subunit (p12E) that is identical to the one found in mature virions. The...

Topics

Amino Acid Sequence
Animals
Biological Transport
CHO Cells
Cell Fusion
Cricetinae
Gene Transfer Techniques
HeLa Cells
Humans
Hydrogen-Ion Concentration
Leukemia Virus, Murine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Fusion

Mice

Molecular Sequence Data

Morphogenesis

Mutation

Peptide Fragments

Proviruses

Source

Open in PubMed Open full text

Identifiers

PMID: 8151784
DOI: 10.1128/JVI.68.5.3220-3231.1994
PMCID: PMC236813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8151784-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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