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Article

Identification of conformational and cold-sensitive mutations in the MuLV envelope protein.

Virology - 1 Aug 2003

O'Reilly Lucille, Roth Monica J

Abstract excerpt

The structure and function of the C-terminal domain of the murine leukemia virus Surface protein (MuLV SU) is not well defined. Passage of chimeric ecotropic-amphotropic MuLV viruses with junctions within the SU C-terminus results in the selection of specific point mutations which improve virus viability and Env function. Point mutations were characterized that alter the conformation of the SU/TM heterodimers on...

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Identifiers

PMID: 12919739
DOI: 10.1016/s0042-6822(03)00244-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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