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Article

Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1993

Lobigs M

Abstract excerpt

Flavivirus protein biosynthesis involves the proteolytic processing of a single polyprotein precursor by host- and virus-encoded proteinases. In this study, the requirement for the proteolytic function of the viral proteinase NS3 for correct processing of a polyprotein segment encompassing the Murray Valley encephalitis virus structural proteins is shown. The NS3-mediated cleavage in the structural polyprotein...

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Identifiers

PMID: 8392191
DOI: 10.1073/pnas.90.13.6218
PMCID: PMC46899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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