Article

Biodistribution of Lentiviral Transduced Adipose-Derived Stem Cells for “Ex-vivo” Regional Gene Therapy for Bone Repair

2023-03-20

Abstract excerpt

<title>Abstract</title> <italic>Ex-vivo</italic> gene therapy has been shown to be an effective method for treating bone defects in preclinical models. As gene therapy is explored as a potential treatment option in humans, an assessment of the safety profile becomes an important next step. The purpose of this study was to evaluate the biodistribution of viral particles at the defect site and various internal o...

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Literature Corpus work: d6bf86eb-6d5f-58b7-98a3-4484773d49b4
DOI: 10.21203/rs.3.rs-2653748/v1

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