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Article

Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal tumorigenesis.

Genes, chromosomes & cancer - 1 Jul 2001

Inoue H, Furukawa T, Sunamura M, Takeda K, Matsuno S, Horii A

Abstract excerpt

Pancreatic ductal carcinoma is one of the malignant diseases with the poorest prognosis. To develop effective methods for better treatment of pancreatic cancer patients, we tried to analyze the course of multistep carcinogenesis of the pancreatic ductal cells. IPMT (intraductal papillary-mucinous tumor) is thought to be one of the premalignant lesions of the pancreas, which would transform into carcinomas. Loss...

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Share to Carcinoma, Pancreatic Ductal
Share to Chromosomes, Human, Pair 18

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Loss of Heterozygosity

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Source

Identifiers

PMID: 11391801
DOI: 10.1002/gcc.1147

Genes

SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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